The blaze gutted an area called "Board Building" at around 1 AM.
Member of Parliament for St. Andrew South Western, Dr. Angela Brown Burke says residents were unable to save their properties.
The number of people killed in Manchester so far this year has now climbed to 46.
This, after gunmen opened fire on patrons inside a bar in Hillside, Knockpatrick last evening, killing one man and wounding another.
Detectives are probing the circumstances that led to the shooting death of two men in Petersfield, Westmoreland yesterday.
Dead are 21-year-old Jevaughn Locke and 36-year-old Kemar Lawson, both of the community.
People's National Party (PNP) President Mark Golding says he does not have any performance issues with his Members of Parliament.
Golding was responding to questions from IRIE FM News about Prime Minister Andrew Holness' push to improve the performance of Members of Parliament after residents raised concerns.
The police have issued a strong warning against motorists travelling to and from the Jamaica Labour Party Conference at the National Arena tomorrow.
Anyone in violation of the provisions of the Road Traffic Act will be prosecuted.